The most recent technology, NGS, allows for 99.99% accuracy in examining all 23 pairs of chromosomes, including sex chromosomes. It is the most sophisticated, enlightening, and trustworthy approach out there.
NGS, which is based on figuring out the DNA sequence, is essentially different from previous PGD techniques in that it offers a more thorough analysis of the genetic composition of the embryos. It enables experts to identify diversity in embryos, for example. Partial anomalies in the embryo’s genetic makeup are known as mosaicism, and they may result in miscarriage or the birth of a child with serious illnesses.
1. Increases the chances of embryo implantation and, consequently, positive outcomes
2. Reduces the risk of miscarriage
3. Decreases the likelihood of failed IVF attempts
4. Lowers the risk of children being born with chromosomal abnormalities
5. Eliminates the need for screening and diagnostic tests during pregnancy, thereby reducing the cost of pregnancy follow-up
A next-generation sequencing (NGS) test called PGT-A examines embryos to check for aneuploidy, which is caused by improperly duplicated, hybridized, or twisted chromosomes. Reproductive endocrinologists can select the highest-quality embryos to transfer and increase the chances of a healthy pregnancy by identifying embryos with the appropriate number of chromosomes.
A specific NGS test called PGT-M can identify single-gene diseases including sickle cell disease and cystic fibrosis. The fertility specialist can utilize this information to find, pick, and select genetically normal embryos, giving the families a chance to have a healthy child.
A type of NGS test called PGT-SR is used to find balanced chromosomal rearrangements that may impact fertility, cause miscarriages, or result in the birth of a child with a genetic defect. Fertility professionals can take part in the well-informed decision-making process on which embryos to transfer when certain structural chromosomal abnormalities are identified.
The IVF environment has been completely changed by next-generation sequencing, which also gives fertility specialists a previously unheard-of grasp of the genetic composition of embryos, enabling them to create more individualized, effective, and successful treatment plans. Our clinic is committed to helping couples and families who want to build a family while protecting the health and safety of both parents and children by utilizing this cutting-edge technology.
If you would like to learn more about how Next-Generation Sequencing can improve your fertility journey, we invite you to schedule a Free consultation with our team of experienced fertility specialists and genetic counselors.
Patients with Known Genetic Conditions
Patients with a History of Pregnancy Loss or IVF Failure
Patients with a Higher Risk of Chromosomal Errors
1. Sample Collection
The NGS process begins with the recovery of a small number of cells, such as those from an embryo biopsy. In order to minimize any disturbance to the embryo’s growth, this biopsy is carried out during the IVF procedure.
2. DNA Extraction and Library Preparation
Following the recovery of the biopsy sample, the DNA is extracted and ready for sequencing. To extract the genetic material and create a library of interrogable DNA sequences, several laboratory techniques are needed.
3. Sequencing
High-throughput sequencing, which uses the newest technologies to swiftly and accurately identify the genetic information present in the sample, is the next step in processing the hybridized DNA library.
4. Data Analysis and Interpretation
Bioinformatic experts then thoroughly review all of the data gathered from the sequencing process, using specialized software and algorithms to find any genetic variations or anomalies on the embryo’s DNA.
Our clinic's location in the Famagusta (Gazimağusa), Glapsides region of Northern Cyprus puts you within easy reach of the area's best swimming beaches, restaurants, and resorts, allowing you to relax and unwind during your stay.
Located in Northern Cyprus, this is the most convenient option and is only a 40-minute drive from our clinic.
Located in the South of Cyprus, this is another popular option depending on your passport and flight availability.
To ensure your experience is completely stress-free from the moment you book your flights, your dedicated Patient Coordinator will manage all of your logistical arrangements. We handle every detail so you can focus on your treatment.
We will arrange for a driver to meet you upon arrival and transport you directly to your accommodation and appointments.
We can recommend and assist with booking your stay from a wide range of high-quality hotels, apartments, and boutique options that meet our standards for comfort and convenience.
From your arrival until your departure, we ensure every detail of your visit is thoughtfully managed.
Simply share your travel plans with your coordinator, and we will handle the rest.
For patients requiring an egg or sperm donor, we have a comprehensive and carefully managed donor programme. The process is governed by strict local regulations that ensure complete donor anonymity.
Our donors undergo rigorous screening, including extensive medical, genetic, and psychological evaluations, to ensure the highest standards of quality and safety. While the donor's identity remains anonymous, you will be provided with a detailed, non-identifying profile which typically includes:
This allows you to choose a donor with characteristics that are important to you while respecting the legal framework of anonymity.
We specialize in making the process seamless for our international patients. Your journey is managed by a dedicated International Patient Coordinator who will be your single point of contact.
After your initial consultation, we will create your bespoke treatment plan.
We offer two flexible pathways for our patients travelling from abroad.
For your convenience, you can begin the initial stages of your treatment at home. We will coordinate with a UK-based clinic for your preliminary scans and tests. You then travel to Cyprus to complete the final stages, requiring a stay of as little as one week for your key procedures. This option is popular as it minimizes your time away from home.
Alternatively, you can choose to undertake your entire treatment cycle with us in Cyprus. This allows you to step away from daily routines and relax in our calm, supportive environment. This all-inclusive pathway typically requires a stay of approximately three weeks.
Whichever pathway you choose, your coordinator will assist with planning your trip, providing recommendations for premium accommodation and organizing private airport transfers. Our goal is to manage all the logistics, allowing you to focus completely on your treatment in a calm, stress-free environment.
This is often the first and most important question we receive. While we are proud of our excellent success rates, which are in line with top European clinics, we believe in providing you with a transparent and realistic perspective. Rather than focusing on a single, generic statistic, we provide a personalized success projection during your initial consultation. This is based on your specific age, medical history, and diagnosis.
Our success is built upon the expertise of our world-class clinicians and embryologists, who utilize state-of-the-art laboratory technology, including AI-driven embryo selection. We are committed to ethical and transparent reporting, ensuring you have the confidence and clarity you need to make an informed decision.
